Hepg2 insulin resistance
WebThe insulin‑induced expression of GLUT2 and p‑GSK‑3 were eliminated by 3DG (80 and 300 ng/ml), in addition to inhibiting the phosphorylation of downstream effectors of the … Web12 apr. 2024 · Screening of in vitro antidiabetic assay in HepG2 cells A glucose uptake assay was conducted in insulin resistance HepG2 (IR-HepG2) cells to establish the antidiabetic activity of the Lc-EAF. IR-HepG2 cells were first generated according to the protocol reported by Saravanakumar et al. ( 2024 ).
Hepg2 insulin resistance
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Web27 jan. 2024 · Elevated free fatty acid (FFA) is a key risk factor for insulin resistance (IR). Our previous studies found that mangiferin could decrease serum FFA levels in obese … Web7 okt. 2024 · PKM2 silencing reversed PA-induced insulin resistance in HepG2 cells. In addition, we showed that PKM2 could interact with STAT3 and activate STAT3 pathway …
WebInsulin-stimulated protein kinase B (Akt/PKB) phosphorylation was measured in high glucose-induced, insulin-resistant HepG2 cells. Similar to 30 μmol/l rosiglitazone, … WebHerein, we first established an insulin-resistant cell model by treating HepG2 cells with 1 × 10 −6 mol L −1 insulin for 24 h. Subsequently, the effects of R3G and R4G on insulin …
Weband AKT in insulin-resistant HepG2 cells in a dose-dependent manner. In addition, the LC-MS/MS results showed that the NBT subfraction contained many active ingre-dients. … WebThe endoplasmic reticulum stress response is associated with insulin resistance-mediated drug resistance in HepG2 cells[J]. Neoplasma. 2015;62(2):180-190 7. Liu X, Li L, Li J. et …
Web目前认为胰岛素抵抗 (insulin resistance，IR)不仅是2型糖尿病的发病基础，也是贯穿多种代谢相关疾病的主线，是心血管疾病、高脂血症、高尿酸血症及代谢综合症的共同病理基 …
Web23 dec. 2024 · Insulin resistance (IR) is likely to induce metabolic syndrome and type 2 diabetes mellitus (T2DM). Gluconeogenesis (GNG) is a complex metabolic process that … fort white florida zip codeWeb26 nov. 2024 · In human hepatoblastoma HepG2 cells, ginkgolic acid C17:1 (20–80 µg/mL in vitro, or 20–80 mg/kg every other day intraperitoneally for 2 weeks) dose-dependently inhibited the cell viability, migration, and invasion, as well as tumor growth in vivo [ 38 ]. fort white florida to jacksonville flWeb12 apr. 2024 · The effect of Lc-EAF treatments on glucose uptake was studied in insulin resistance HepG2 cells (IR-HepG2). Further, the antidiabetic effect of Lc-EAF in … fort white florida schoolsWeb1 okt. 2010 · HepG2, hepatocellular carcinoma cells, are used in drug toxicity studies and have also been explored for bioartificial livers. For these applications, the cells are under … diphthong listWeb2 dagen geleden · HepG2 cells were treated with FFA to establish the insulin resistance model. Then, the cells were treated with SC79 (10 μmol/L), CA (10, 1, and 0.1 μmol/L), CA4G (10, 1, and 0.1 μmol/L), FA (10, 1, and 0.1 μmol/L), or FA4G (10, 1, and 0.1 μmol/L) respectively for 2 h, according to our preliminary experiment (data not shown). fort white florida real estate for saleWeb15 jan. 2015 · Palmitate induces insulin resistance in human HepG2 hepatocytes by enhancing ubiquitination and proteasomal degradation of key insulin signaling … fort white florida vacation rentalsWeb1 dec. 2015 · Insulin resistance is a hormone that facilitates the transport of blood sugar (glucose) from the bloodstream into cells throughout the body for use as fuel and is the … fort white fl radar map