WebMurine PC (FC1245) and stellate (ImPaSC) cells were cultured to generate organoids that recapitulated the histological organization of PC with the formation of ducts by epithelial … WebOct 24, 2015 · Orthotopic transplantation of FC1245 cells into syngeneic mice gave rise to pancreatic carcinoma with metastases in liver, spleen, and kidney (Supplementary Table 3). Upon treatment of the animals with crizotinib, both tumor growth and metastasis were inhibited (Figure 3B and C). Most importantly, mv6pep treatment also reduced primary …
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